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药物化学教研室

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赵龙

作者: 发布日期:2025-01-17 访问:

赵龙 博士 讲师

联系方式:zhaolong@bbmu.edu.cn

教育经历

2008.092012.06 安徽师范大学,应用化学,学士,导师:周双六教授;

2012.092015.06 上海大学,有机化学,硕士,导师:吴小余教授;

2015.092018.09 德国亚琛工业大学,有机化学,博士,导师:Dieter Enders(德国科学院院士)

科研及工作经历

2019.042021.06 深圳大学,高等研究院,博士后

2022.11至今,蚌埠医科大学,药学院,讲师

研究方向

不对称催化合成药物分子及其活性评价、天然产物;DNA荧光探针

所获奖励

硕士研究生国家奖学金;国家公派留学基金;广东省珠江人才-海外博士后引进

代表性论文:

1. Meng-Fan Xu, Ke Zhong, Jing Zhu, Jie Chen, Fang Liu, Feng Ding, Cheng-Zhu Wu* and Long Zhao*. Novel bakuchiol derivatives inhibits migration and invasion of non-small cell lung cancers by suppressing epithelial-to-mesenchymal transition. Journal of Enzyme Inhibition and Medicinal Chemistry. 2024, submmited.

2. Jie Chen, Long Zhao(共同一作), Meng-Fan Xu, Di Huang, Xiao-Long Sun, Yu-Xin Zhang, Hong-Mei Li and Cheng-Zhu Wu*. Novel isobavachalcone derivatives induce apoptosis and necroptosis in human non-small cell lung cancer H1975 cells. Journal of Enzyme Inhibition and Medicinal Chemistry. 2024, 39, 2292006.

独立工作之前:

1. Long Zhao, Farid Ahmed, Yating Zeng, Weiqing Xu, Hai Xiong*. Recent Developments in G‑Quadruplex Binding Ligands and Specific Beacons on Smart Fluorescent Sensor for Targeting Metal Ions and Biological Analytes. ACS Sensors. 2022, 7, 2833-2856.

2. Long Zhao, Farid Ahmed, Hai Xiong*. An excimer ‘ON-OFF’ switch based on telomeric G-quadruplex and rGO for trace thrombin detection. Chinese Chemical Letters. 2022, 33, 4243-4247.

3. Long Zhao, Gerhard Raabe, and Dieter Enders*. Asymmetric Synthesis of 2,2-Disubstituted Benzofuranones through an Organocatalytic Alkylation with Nitroallylic Acetates. Synthesis, 2019, 51, 1391-1398.

4. Long Zhao, Sun Li, Lei Wang, Shun Yu, Gerhard Raabe, and Dieter Enders*. Asymmetric Synthesis of Cyclopentene-Fused Tetrahydroquinolines via N-Heterocyclic Carbene Catalyzed Domino Reactions. Synthesis, 2018, 50, 2523-2532.

5. Long Zhao, Beibei Guo, Guanxin Huang, Jie Chen, Weiguo Cao, and Xiaoyu Wu*. Enantioselective Formation of 3-Substituted Indolinoazepines via Organocatalyzed Conjugate Addition of Indoloazepines to Propargyl Aldehyde. ACS Catal. 2014, 4, 4420-4424.

6. Long Zhao, Guanxin Huang, Beibei Guo, Lijun Xu, Jie Chen, Weiguo Cao, Gang Zhao, * and Xiaoyu Wu*. Diastereo- and Enantioselective Propargylation of Benzofuranones Catalyzed by Pybox-Copper Complex. Org. Lett. 2014, 16, 5584-5587.